FAKTOR YANG BERHUBUNGAN DENGAN TUBERCULIN SKIN TEST POSITIF PADA PETUGAS KESEHATAN DI RUMAH SAKIT DI KOTA JEMBER

Factors Related to Tuberculin Skin Test Positive in Healthcare Workers at Hospitals in Jember City

Authors

  • Hamidah Retno Wardani master of tropical medicine, faculty of medicine, universitas airlangga
  • Ni Made Mertaniasih
  • Soedarsono Soedarsono

DOI:

https://doi.org/10.33023/jikep.v6i2.649

Keywords:

Tubercullin skin test, healthcare worker, risk factors

Abstract

Tuberkulosis merupakan penyakit infeksi yang tidak hanya ada di komunitas tetapi juga di tempat kerja seperti pelayanan kesehatan. Petugas kesehatan di Rumah Sakit memiliki risiko tinggi terpajan droplet yang mengandung Mycobacterium tuberculosis. Penelitian ini bertujuan untuk mendeteksi positif tuberculin skin test pada petugas kesehatan di Rumah Sakit di Kota Jember. Penelitian ini menggunakan cross-sectional, pada bulan Januari sampai Maret 2020 di dua rumah sakit di kota jember. Masing-masing petugas kesehatan di unit perawatan TB dan unit perawatan non TB dievaluasi menggunakan Tuberculin skin test dengan cut-off ? 10 mm untuk positif tuberculin skin test. Deteksi positif tuberculin skin test terjadi pada 77 (60.2%) petugas kesehatan dari total 128 petugas kesehatan. Faktor risiko jenis kelamin laki-laki (p-value=0.329; OR=1.425; CI=0.6499-2.904), rentang usia (p-value=0.676; OR=0.740; CI=0.176-3.101), BMI (p-value=0.539), riwayat merokok (p-value=0.132; OR=2.059; CI=0.796-5.330), riwayat kontak TB di keluarga (p-value=0.481; OR=1.555; CI=0.452-5.348), riwayat bekerja di unit TB (p-value=0.692; OR=1.154; CI=0.568-2.344) tidak memiliki hubungan bermakna dengan reaksi tuberculin skin test positif. Reaksi tuberculin skin test positif dengan prevalensi yang tinggi terjadi pada petugas kesehatan yang berisiko meningkatkan risiko terjadinya TB aktif pada petugas kesehatan di Rumah Sakit di Jember. Dibutuhkan suatu program untuk mencegah terjadinya TB pada petugas kesehatan.   

 

Kata kunci: Tuberculin skin test; petugas kesehatan; faktor risiko

Downloads

Download data is not yet available.

References

Lacerda NB, Temoteo CA, Figueiredo MRM, Luna DT, Sousa AN, Abreu C, 2014. Individual and social vulnerabilities upon acquiring tuberculosis: A literature systematic review. Int Arch Med, 7:35.

Iroezindu MO, Ofondu EO, Mbata GC, van Wyk B, Hausler HP, Dh A, 2016. Factors associated with prevalent tuberculosis among patients receiving highly active antiretroviral therapy in a Nigerian tertiary hospital. Ann Med Health Sci Res, 6:120–8.

Tudor C, Van der Walt ML, Margot B, Dorman SE, Pan WK, Yenokyan G, et al. Occupational risk factors for tuberculosis among healthcare workers in Kwazulu-Natal, South Africa, 2016. Clin Infect Dis, 62(Suppl 3):S255–61.

Salehi M, Mood B S, Metanat, 2016. Positive tuberculin skin test among health care workers: prevalence and risk factors in teaching hospitals of a highly endemic region for tuberculosis, Zahedan, Iran. International Journal Infectious, doi:10.17795/iji-36158.

Zhou F, Zhang L, Gao L, Hao Y, Zhao X, Liu J, Lu J, Li X, Yang Y, Chen J, Deng Y, 2014. Latent tuberculosis infection and occupational protection among health care workers in two types of public hospital in China. PLoS ONE, doi:10.1371/journal.pone.0104673.

Centers of Disease Control and Prevention. Tests for TB infection: tuberculin skin test (TST) (Serial Online) 2014 (Cited 2019 August 1). Available from https://www.cdc.gov/tb/publications/ltbi/diagnosis.htm#two Step TST Testing.

Severo KGP, Oliveira JdS, Carneiro M, Valim ARM, Krummenauer EC, Possuelo LG, 2011. Latent tuberculosis in nursing professional of a Brazilian hospital. Journal of Occupational Medicine and Toxicology, 6:15.

Tang P, Johnston J, 2017. Treatment of latent tuberculosis. Curr Treat Options Infect Dis, DOI 10.1007/s40506-017-0135-7.

CDC. TB laten : a guide for primary health care providers (Serial Online) 2019 (Cited 2019 August 1) Available from:https://www.cdc.gov/tb/publications/ltbi/treatment.htm#two.

World Health Organisation (WHO), Global Tuberculosis Report 2014 (Serial Online) 2014 (Cited 2019 August 1). Available from: https://www.who.int/tb/publications/global_report/gtbr14_main_text.pdf.

Simon AK, Hollander GA. McMichael A, 2015. Evolution of the immune system in humans from infancy to old age. Proc R Soc B, 282(1821), p.20143085.

Deng Y, Liu Y, Li Y, Jing H, Wang Y, Li X, Xu L, 2019. Isolation measures and protection awareness are significant for TB laten : a cross-sectional study on T-SPOT.TB among health care workers in China. Epidemiology of Infection, Doi.org/10.107/s0950268818002777.

Erawati M, Andriany M, 2020. The prevalence and demographic risk factors for latent tuberculosis infection (LTBI) among healthcare workers in Semarang, Indonesia. Journal of Multidisciplinary Healthcare, 13 197-206.

Pratomo IP, Burhan E, Tambunan V, 2012. Malnutrisi dan tuberkulosis. J Indon Med Assoc, 62(230), 7-12.

Zhang H, Li X, Xin H, Li H, Li M, Lu W, Bai L, Wang X, Liu J, Jin Q, Gao L, 2017. Association of body mass index with the tuberculosis infection: a population-based study among 17796 adults in rural China. Scientific reports, doi: 10.1038/srep41933.

Cegielski JP, McMurray DN, 2004. The relationship between malnutrition and tuberculosis: evidence from studies in humans and experimental animals. The International Journal of Tuberculosis and Lung Disease, 8(3):286-98.

Chen C, Zhu T, Wang Z, Peng H, Kong W, Zhou Y, Shao Y, Zhu L, Lu W, 2015. High latent TB infection rate and associated risk factor in the Eastern China of low TB incidence. PLoS ONE, 10 (10): e0141511.

Feng Y, Kong Y, Barnes PF, Huang F-F, Klucar P, Wang X, Samten B, Sengupta M, Machona B, Donis R, Tvinnereim A R, Shams H, 2011. Exposure to cigarette smoke inhibits the pulmonary T-Cell response to influenza virus and mycobacterium tuberculosis. Infection and Immunity, 79(1):229–37. pmid:20974820.

Robbins CS, Dawe DE, Goncharova SI, Pouladi MA, Drannik AG, Swirski FK, Cox G, Stampfli MR, 2004. Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness. Am J Respir Cell Mol Biol, doi:10.1165/rcmb.2003-0259OC.

Migliori GB, Nardell E, Yedilbayev A, D’Ambrosio L, Centis R, Tadolini M, Boom MVD, Ehsani S, Sotgiu G, Dara M, 2019. Reducing tuberculosis transmission: a consensus document from the world health organization regional office for Europe. European Respiratory Journal, doi: 10.1183/13993003.00391.

Allyn PR, Brewer TF. Guide to infection control in the healthcare setting (Serial Online) 2018 (Cited 2020 September 9). Available from: International Society for Infectious Disease:https://isid.org/wpcontent/uploads/2019/07/ISID_GUIDE_TUBERCULOSIS.pdf

Nonghanpithak D, Reechaipichitkul W, Chaiyasung T, Faksri K, 2016. Risk factors for TB laten among health-care workers in northeastern Thailand. South East Asia Tropical Medicine and Public Health, Vol 47 No. 6.

Borroto S, Gamez D, Diaz D, Martinez Y, Ferre A I, Velasquez Y, Lianes E, Gonzales, 2011. TB laten among health care workers at a general hospital in Santiago de Cuba. Int J Tuberculosis Lung Disease, 15: 1510-4.

Powell K, Han D, Hung NV, Vu T, Sy DN, Trinh TT, Le TC, Do K, Oetmann JE, Whitehead S, 2011. Prevalence and risk factors for tuberculosis infection among personnel in two hospitals in Viet Nam. 9 Int J Tuberc Lung Dis, 15: 1643.

He GX, Wang L X, Chai S J, Klena J D, Cheng SM, Ren YL, Ren PL, Gao F, Li YY, He GM, Li JB, Rao C, Varma JK, 2012. Risk factors associated with tuberculosis infection among health care workers in Inner Mongolia, China. International Journal Tuberculosis Lung Disease, 16(11):1485-91.

Zhang X, Jia H, Liu F, Pan L, Xing A, Gu S, Du B, Sun Q, Wei R, Zhang Z, 2013. Prevalence and risk factors for latent tuberculosis infection among health care workers in China: a cross-sectional study. PLoS ONE, 8: e66412.

Park JS, 2018. The prevalence and risk factors of latent tuberculosis infection among health care workers working in a tertiary hospital in South Korea. A Journal of Clinical Medicine, 81(4):274-280.

Yoon C, Oh SY, Lee JB, Kim M, Seo Y, Yang J, Bae K, Hong S, Yang E, Kim HJ, 2017. Occupational risk of TB laten in health workers of 14 military hospital. Journal Korean Medical Science, doi.org/10.3346/jkms.2017.32.8.1251.

Published

2020-09-30

How to Cite

Retno Wardani, H., Mertaniasih, N. M., & Soedarsono, S. (2020). FAKTOR YANG BERHUBUNGAN DENGAN TUBERCULIN SKIN TEST POSITIF PADA PETUGAS KESEHATAN DI RUMAH SAKIT DI KOTA JEMBER: Factors Related to Tuberculin Skin Test Positive in Healthcare Workers at Hospitals in Jember City. Jurnal Ilmiah Keperawatan (Scientific Journal of Nursing), 6(2), 261-267. https://doi.org/10.33023/jikep.v6i2.649